thats like asking, how should i organize my underwear drawer
the main screen for me is phone and message related..
main screen.. .browser, gmail, handcent (sms), market, settings, maps, pwr control widget, and picture frame in the middle of my kid..
right screen:
two folders, starred contacts, games, photos, camcorder, camera, pandora, gstrings (guitar tuner), youtube... small music widget
next screen to the right: bookmarks widget
next to the right: empty
left of home: small calendar widget, and downloaded frequently used apps, (acar, ak notepad, pdanet, keeper, engadget, Astro, wikimobile)
clock icon for my alarm, footprints
next left: big weather widget
next left: nothing.