I'm having a horrible time with the power button but I've got it solved now. I'm used to the corner power button of the OG Droid but imo, once I locate the HTC Thunderbolt's power button, it's easier to press than my OG Droid. It's getting past that mental memory location of my OG Droid's power button that is bothering me.
I got a no-name case from Verizon yesterday and no matter what I do, it's impossible to hit the power button. Annoyed me so much I think I'm going to go nekkid with the Thunderbolt like I did with my Droid.