Moto droid here.
Phone dial unlock screen garbles up during landscape mode, IE I wake up my phone usually by opening up the keyboard.
The bottom touch screen buttons *back home menu search* seem to be unresponsive now too at times.
Battery life is pretty bad compared to what I got before I flashed from 2.2.1 stock.
Get at least one reboot a day. Ususally trying to wake phone up the bottom touch buttons will light up then turn back off then the phone restarts.
Accounts don't sync even though they are auto sync enabled. I found this out by trying to send a dev an email through the market and I got a screen from the OS saying my account wasn't on auto sync of which it was. I had to manually refresh/sync for it to work and all a sudden I had gmail emails.
Suggestion: I'm sure you're already doing this but have the UD Options in the list with the rest of the phone settings list.