I use Godaddy Exchange email service as my primary PIM service with Outlook 2010 on desktop PC and OWA sometimes when using third party PCs.
Never had any problems configuring exchange on my Blackberry (Enterprise Activation), but when I tried setting up Droid Pro - auto detection seems not to work there.
In case you try to configure exchange yourself, here is an excellent guide: Using an Android Mobile Device with Hosted Exchange - Search the Go Daddy Help Center
After initial sync that took a while (I have around 1200 contacts and several hundred of calendar entries) everything seems to be working fine except I cannot get Droid Pro to pull contact pictures from the exchange server (I don't use facebook).
Are there any hacks, tweaks or anything else to get 2.2 Android handle MS Exchange on a similar level as Blackberry does?