They pretty much have the same specs and the companies are both very well known in the business. That means for me (company bias, and small nit picky things out of the way)
Vigor has beats audio going for it.
The Nexus obviously has the fact that it has ICS and it's a pure Google device going for it.
I think the prime wins.
Those are just the main things, but there are a lot more things. Samsung makes better screens. HTC had bad battery life, but has Sense which some people love. But I think it really boils down to Vanilla ICS vs. Beats, and it's vanilla by far for me. I would be happy with either phone though! :-P