I have been searching the board for a few days, and have not found a similar issue, my apologies if I've overlooked a thread/fix for this.
The problem began after attempting OTA .340 update, the phone was rooted via Z4 root before attempting the OTA. OTA update failed. I then did a factory reset, stock recovery, clear data, cache, etc.
The issue: The home screen comes up blank. The lock screen shows my previous background image (a pic I took, not a stock image). Once I unlock the screen, all I have is a blank, black screen. The notification bar is in place, I can receive calls and emails, use the web, can place calls via the voice dialer, things of that sort. I have no icons, cannot access the application menu, settings, etc.
Today I ran RSD Lite and attempted to install 2.1, but that update fails also. RSD lite gives failure reason as: "Failed flashing process. Phone : Phone not compatible with multi-interface super-file".
I believe that is all relevant info. Any suggestions before heading back to the store? I would prefer to fix this myself as opposed to attempting to get a replacement/fix from the big red V.