Kwyjibo is a word made up by Bart during a game of Scrabble with his family. In the episode "Bart the Genius," Bart puts "kwyjibo" on the board, scoring 116 points (22 points, plus Triple Word Score, plus 50 points for using all seven of his letters). When Homer demands Bart say what a kwyjibo is, Bart replies, "A big, dumb, balding North American ape… with no chin." Marge adds in, "…and a short temper." At this point, Homer chases Bart away, causing him to exclaim, "Uh oh! Kwyjibo on the loose!"
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It all makes sense now.
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Yeah going to close this one down.