The RAZR will have ICS before you know it, and the Rezound maybe sooner being unlocked. Aside from people who obsess over fonts and icon colors, I'm finding fewer and fewer reasons to recommend the GNex.
Some people act like not being unlocked/flashing is going to leave your device behind, but ICS is pretty polished so I think that's overrated. Even if you never got another update beyond ICS, it wouldn't remotely be like being stuck on 2.0 or 2.1. Froyo was a big leap and ICS is a big leap, but I can't see another such big leap for Android outside of some features that are already done well with various apps in the market (i.e. Locale, Tasker, a number of widgets).
I think the next big leap for Android will be laptop replacement capability (something far beyond that Webtop gimmick). And NONE of this current crop of phones have near the power to do that, so you won't be missing anything.